تفاصيل الوثيقة
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نوع الوثيقة |
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مقال في مجلة دورية |
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عنوان الوثيقة |
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Dysembryoplastic Neuroepithelial Tumor (DNT): Morphological and Immunohistochemical Features Dysembryoplastic Neuroepithelial Tumor (DNT): Morphological and Immunohistochemical Features |
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لغة الوثيقة |
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الانجليزية |
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المستخلص |
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Dysembryoplastic neuroepithelial tumor is a rare mixed neuronalglial
tumor. The recognition and correct diagnosis of dysembryoplastic
neuroepithelial tumor is important because this tumor is curable by excision.
The records of the Pathology Department at King Faisal Specialist Hospital
and Research Center, Jeddah, Saudi Arabia, were reviewed for cases that were
histologically diagnosed as dysembryoplastic neuroepithelial tumor between
2000 and 2007; five cases were found. The clinical, radiological, histological
and immunohistochemical findings were reviewed. The ages ranged between
9 and 25 years. There were 2 males and 3 females. All patients were
diagnosed with epilepsy. Three patients had temporal tumor and the other two
had frontal tumors. Radiological evaluation showed non-enhancing mass
without mass effect or vasogenic edema. All five cases were characteristically
composed of small round oligodendroglia-like cells, astrocytes and mature
neurones in varying proportions. Immunocytochemistry for glial fibrillary
acidic protein and neuronal markers (neuron-specific enolase; and
synaptophysin) highlights the astrocytic and neuronal components. The
recognition of this tumor is very important because it is a surgically curable
lesion with excellent prognosis. Pathologists need to be familiar with the
characteristic histopathological findings to avoid unnecessary overtreatment
by radiotherapy or chemotherapy. |
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ردمد |
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0969-711 |
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اسم الدورية |
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JKAU: Med. Sci., |
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المجلد |
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14 |
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العدد |
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3 |
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سنة النشر |
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2007 هـ
2007 م |
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نوع المقالة |
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مقالة علمية |
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تاريخ الاضافة على الموقع |
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Sunday, April 11, 2010 |
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الباحثون
| جودة المغربي | Al-Maghrabi, Jaudah | باحث رئيسي | دكتوراه | |
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الرجوع إلى صفحة الأبحاث
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